Product Overview
Melanotan 2 (MT-2) 10mg is a synthetic peptide analog of the naturally occurring alpha-melanocyte-stimulating hormone (α-MSH). Developed for advanced laboratory research, MT-2 is a potent, non-selective melanocortin receptor agonist (targeting MC1R, MC3R, MC4R, and MC5R).
This research-grade peptide is primarily studied for its role in melanogenesis (the biological production of melanin) and its complex interactions with physiological systems involving appetite, metabolism, and sexual function. Our MT-2 is supplied as a 10mg lyophilized powder, ensuring maximum stability and purity for in vitro and in vivo research models.
Mechanism of Action: Receptors and Signaling
Melanotan II mimics the effects of natural α-MSH but with significantly enhanced biological activity and resistance to enzymatic degradation. Its primary mechanism involves the activation of several melanocortin receptor subtypes:
- MC1R Activation: Stimulates melanocytes to produce melanin, facilitating research into UV-independent pigmentation.
- MC4R MC3R Interactions: These receptors are heavily involved in the regulation of energy homeostasis, appetite suppression, and sexual arousal mechanisms.
- Enhanced Stability: Featuring a cyclic structure, MT-2 has a longer half-life than natural hormones, making it ideal for extended research protocols.
Primary Research Applications of MT-2
Researchers utilize Melanotan 2 10mg to explore a wide array of physiological and pharmacological pathways:
- Melanogenesis Skin Research: Investigating melanin production and its protective effects against UV radiation in experimental models.
- Sexual Health Studies: MT-2 is widely studied in models of erectile dysfunction (ED) and libido modulation due to its activation of central melanocortin receptors.
- Metabolic Appetite Regulation: Exploring the peptide's role in weight management, energy expenditure, and appetite suppression.
- Neuroprotective Signaling: Ongoing research investigates the anti-inflammatory and neuroprotective potential of melanocortin activation in the central nervous system.
Storage & Reconstitution Guidelines
To preserve the integrity of the Melanotan 2 peptide:
- Long-term Storage (Lyophilized): Store unopened vials at -20°C or below.
- Short-term Storage: Refrigerate at 2°C–8°C for up to 24 months in powder form.
- Reconstitution: Use bacteriostatic water for reconstitution. Once dissolved, store the solution at 2°C–8°C and use within 20–30 days for optimal research consistency.
- Handling: Avoid excessive agitation of the vial after reconstitution to prevent peptide degradation.
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